Article
Non-mutagenicity of 27 aliphatic acrylate esters in the Salmonella-microsome test.
Mutation research - 1 Jan 2000
Waegemaekers T H, Bensink M P
Abstract excerpt
The mutagenicity of 27 acrylate esters was assessed in the Salmonella-microsome assay. Methyl, ethyl, butyl, t-butyl, pentyl, neopentyl, hexyl acrylate and methacrylate and 2-hydroxyethyl methacrylate were tested; furthermore ethanediol, butanediol, pentanediol, neopentanediol, hexanediol and diethyleneglycol diacrylate and dimethacrylate. None of these 27 acrylate esters appeared to be mutagenic in the standard...
Topics
- Acrylates
- Animals
- Biotransformation
- Esters
- Microsomes, Liver
- Mutagenicity Tests
- Mutagens
- Mutation
- Rats
- Salmonella typhimurium
- Species Specificity
- Structure-Activity Relationship