Mutagenicity of hexachlorobutadiene, perchlorobutenoic acid and perchlorobutenoic acid chloride.

doi:10.1016/0165-1218(84)90096-x

Back to search

Article

Mutagenicity of hexachlorobutadiene, perchlorobutenoic acid and perchlorobutenoic acid chloride.

Mutation research - 1 Jan 2000

Reichert D, Neudecker T, Schütz S

Abstract excerpt

Hexachloro(1,3)butadiene (HCBD) is a well known environmental contaminant. The nephrocarcinogenic potential of HCBD has been shown in long-term studies with rats. Experiments were performed to assist in determining whether this effect is mediated by epigenetic or genotoxic mechanisms and to compa...

Topics

Animals
Biotransformation
Butadienes
Fungicides, Industrial
Hydrocarbons, Chlorinated
Microsomes, Liver
Mutagenicity Tests
Mutagens
Mutation
Salmonella typhimurium
Structure-Activity Relationship

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.