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Article

Damaged-site independent mutagenesis of phage lambda produced by inducible error-prone repair.

Biochimie - 1 Jan 2000

Quillardet P, Devoret R

Abstract excerpt

The existence of damaged-site independent mutagenesis is confirmed here by scoring the appearance of clear-plaque (c-) or virulent (vir) forward mutations on intact (non-irradiated) phage lambda grown on UV-irradiated E. coli K12 hosts. The mutation frequency was measured as a function of the incubation time between the occurrence of host DNA lesions and phage infection. The time course of mutagenesis of intact...

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PMID: 6215954
DOI: 10.1016/s0300-9084(82)80130-2

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