Article
Mechanism of SOS-induced targeted and untargeted mutagenesis in E. coli.
Biochimie - 1 Jan 2000
Maenhaut-Michel G
Abstract excerpt
This paper retraces the evolution of hypotheses concerning mechanisms of SOS induced mutagenesis. Moreover, it reports some recent data which support a new model for the mechanism of targeted and untargeted mutagenesis in E. coli. In summary, the SOS mutator effect, which is responsible for untargeted mutagenesis and perhaps for the misincorporation step in targeted mutagenesis, is believed to involve a fidelity...
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