Article
The genetic control of bufuralol metabolism in man.
European journal of drug metabolism and pharmacokinetics - 1 Jan 2000
Dayer P, Balant L, Courvoisier F, Kupfer A, Kubli A, Gorgia A, Fabre J
Abstract excerpt
Bufuralol (Ro 3 - 4787, Angium) is a non selective beta-adrenoceptor blocking drug with some degree of sympathomimetic action and a longer duration of action than propranolol. Plasma concentrations of bufuralol and 1'-hydroxybufuralol, its main blood derivative which shows similar beta-adrenocept...
Topics
- Adrenergic beta-Antagonists
- Biotransformation
- Ethanolamines
- Female
- Humans
- Kinetics
- Male
- Phenotype
