Article
Further characterization of repair of 8-methoxypsoralen crosslinks in UV-excision-defective Escherichia coli.
Mutation research - 1 Jan 2000
Bridges B A
Abstract excerpt
Evidence was previously presented for a new pathway for the repair of 8-methoxypsoralen DNA crosslinks. The pathway, which is independent of the uvrA gene but deficient in rep mutants, has now been further characterized and shown to be more active in minimal than in nutrient growth media and to be inhibited by acriflavine. Although crosslink repair is much reduced in recA bacteria, some still occurs as judged by...
Topics
- Bacterial Proteins
- DNA Repair
- Dose-Response Relationship, Radiation
- Escherichia coli
- Genes
- Genes, Bacterial
- Genotype
- Methoxsalen
- Phenotype
- Ultraviolet Rays