Article
DNA damage by 8-methoxypsoralen plus near ultraviolet light (PUVA) and its repair in Escherichia coli: genetic analysis.
Mutation research - 1 May 1991
Holland J, Holland I B, Ahmad S I
Abstract excerpt
Mutants of Escherichia coli, hyper-resistant and sensitive to 8-methoxypsoralen plus near ultraviolet light (PUVA) have been isolated and studied. Results show that a mutation, located at 57.2 min on the linkage map of E. coli, is responsible for the hyper-resistant phenotype. It is also responsible for the synthesis of a 55-kdal protein in high concentrations. In a wild-type cell the synthesis of this enzyme is...
Topics
- Bacterial Proteins
- Chromosome Mapping
- DNA Damage
- DNA Repair
- DNA, Bacterial
- Escherichia coli
- Genes, Bacterial
- Genetic Complementation Test
- Methoxsalen
- Microbial Sensitivity Tests
- Molecular Weight