Article
Magnetic resonance diffusion-derived vessel density (DDVD) as a valuable tissue perfusion biomarker for isocitrate dehydrogenase genotyping in diffuse gliomas.
BMC medical imaging - 6 Mar 2025
Ni Chen-Xi, Lin Ruo-Lan, Yao Dian-Qi, Ma Fu-Zhao, Shi Yu-Ting, He Ying-Ying, Song Yang, Yang Guang, Jiang Ri-Feng, Wáng Yì Xiáng J
Abstract excerpt
BACKGROUND: Determining isocitrate dehydrogenase (IDH) mutation is crucial for glioma clinical management. MR diffusion-derived 'vessel density' (DDVD) offers non-invasive tissue perfusion evaluation within the tumor microenvironment. The study attempts to distinguish IDH genotypes of diffuse gliomas using DDVD in whole tumor parenchyma and its habitats. METHODS: This study enrolled 63 patients with diffuse...
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