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Article

Spectral Analysis Based on Hemodynamic Habitat Imaging Predicts Isocitrate Dehydrogenase Status and Prognosis in High-Grade Glioma.

World neurosurgery - 1 Jul 2023

Qiao Jinguo, Wu Hao, Liu Jiachen, Kang Houyi, Wang Shunan, Fang Jingqin, Zhang Junfeng, Zhang Weiguo

Abstract excerpt

BACKGROUND: The intratumoral heterogeneity of high-grade gliomas (HGGs) is associated with isocitrate dehydrogenase (IDH) status and prognosis, which can be established by quantitative radioanalysis of spatial tumor habitats. Therefore, we designed a framework for tackling tumors based on spatial metabolism using the hemodynamic tissue signature (HTS), focusing on metabolic changes in tumor habitat to predict IDH...

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PMID: 37028478
DOI: 10.1016/j.wneu.2023.03.136

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