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Article

Bidirectional associations between brain functional networks and sleep disorders: A bidirectional Mendelian randomization study.

Medicine - 18 Sept 2026

Dong Lixia, Wei Hanliang, Wu Tingting, Dong Junxing, Fan Tengteng, Mi Weifeng, Wang Sanwang

Abstract excerpt

The prevalence of sleep disorders has been rising over recent decades. Sleep disorders are frequently associated with disruptions in resting-state functional brain networks. Despite these associations, the direction and genetic basis of the relationships between brain functional networks and sleep disorders remain unclear. Utilizing bidirectional two-sample Mendelian randomization (MR), we examined bidirectional...

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Topics

Humans
Mendelian Randomization Analysis
Magnetic Resonance Imaging
Sleep Wake Disorders
Brain
Nerve Net

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Phenotype

Female

Genetic Predisposition to Disease

Male

Source

Open in PubMed Open full text

Identifiers

PMID: 42760706
DOI: 10.1097/MD.0000000000050778
PMCID: PMC13593271

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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