Article
[Modern approaches to the genetics of depression: scopes and limitations].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2021
Kasyanov E D, Rukavishnikov G V, Kibitov A A, Malyshko L V, Neznanov N G, Kibitov A O, Mazo G E
Abstract excerpt
SUMMARY: Recent findings in candidate genes for depression showed significant replication failures and thus appeared irrelevant. Much of the earlier studies' limitations can be overcome by the strategy of genome-wide association studies (GWAS), which aims to identify associations between different genomic variants and phenotypic traits without pathophysiological hypotheses application. With the use of such...
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