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Article

Impact of aldehyde dehydrogenase 2 polymorphism on lipid profile alterations in alcohol-abstinent adolescents stratified by steatotic liver disease status.

Environmental health and preventive medicine - 1 Jan 2026

Kado Akira, Inoue Yukiko, Moriya Kyoji, Tsutsumi Takeya, Koike Kazuhiko, Fujishiro Mitsuhiro, Yanagimoto Shintaro

Abstract excerpt

BACKGROUND: Single-nucleotide polymorphism in aldehyde dehydrogenase 2 (ALDH2) is associated with metabolic dysfunction-associated steatotic liver disease (MASLD). However, this association in alcohol-abstinent individuals remains unknown. We assessed SLD and genotype-inferred ALDH2 activity (ALDH2 activity) in alcohol-abstinent adolescents to explore the association between ALDH2 activity and metabolism-related...

Read the complete abstract on PubMed

Topics

Humans
Aldehyde Dehydrogenase, Mitochondrial
Male
Female
Adolescent
Cross-Sectional Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Fatty Liver

Lipids

Genotype

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 42732941
DOI: 10.1265/ehpm.26-00078
PMCID: PMC13585472

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

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