Article
Evaluation of HNF1B, KLK3, ELAC2, TMPRSS2-ERG, and CTNNB1 polymorphisms associated with prostate cancer in samples of patients from HUPE-UERJ.
The Prostate - 1 Feb 2024
Menezes Raphaela Dos Santos, Dornas Maria Cristina, Campos Carlos Frederico Ferreira, Rodeiro Daniela Bouzas, Carrerette Fabricio Borges, Oliveira Romulo Vianna, de Souza Brenda Amaral, Alves de Souza Carvalho Gabriele, Brito Ingrid Alexandre de Abreu, Silva Dayse Aparecida, Damião Ronaldo, Porto Luís Cristóvão
Abstract excerpt
PURPOSE: Prostate cancer (PCa) is the leading cause of death among men in 48 countries. Genetic alterations play a significant role in PCa carcinogenesis. For the hypothesis of this research, five unique polymorphisms (SNP) were investigated in different genes that showed to be associated in different ways with PCa: rs4430796, rs2735839, rs4792311, rs12329760, and rs28931588, respectively for the genes HNF1B,...
