Association of PCSK9 and CCL22 gene polymorphisms with myocardial infarction in a South Indian population.

doi:10.1007/s10142-026-02031-7

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Article

Association of PCSK9 and CCL22 gene polymorphisms with myocardial infarction in a South Indian population.

Functional & integrative genomics - 1 Sept 2026

Chandra Sekar Praveen Kumar, Govindaraj Ashok, Veerabathiran Ramakrishnan

Abstract excerpt

Myocardial infarction (MI) remains a major global cause of morbidity and mortality, with a particularly high burden among individuals with type 2 diabetes mellitus (T2DM). Host genetic factors play a significant role in modulating individual susceptibility to MI by influencing lipid metabolism and immune-mediated inflammatory pathways. The proprotein convertase subtilisin/kexin type 9 (PCSK9) gene is a key...

Read the complete abstract on PubMed

Topics

Humans
Proprotein Convertase 9
Myocardial Infarction
India
Polymorphism, Single Nucleotide
Male

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Middle Aged

Female

Genetic Predisposition to Disease

Chemokine CCL22

Case-Control Studies

Diabetes Mellitus, Type 2

South Asian People

Source

Open in PubMed

Identifiers

PMID: 42678476
DOI: 10.1007/s10142-026-02031-7

Genes

PCSK9
CCL22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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