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Article

PCSK9 gene Polymorphism and Assessment of Cardiovascular Risk and Prognosis in Patients With Hyperlipidemia: A Retrospective Cohort Study.

Journal of clinical hypertension (Greenwich, Conn.) - 1 Aug 2025

Aizezi Aibibanmu, Meng Fanhua, Li Xiaolei, Li Yanpeng, Abuzhalihan Jialin, Liu Fen, Gai Mintao, Adi Dilare, Ma Yi-Tong

Abstract excerpt

Proprotein convertase subtilisin/kexin type 9 (PCSK9) polymorphisms exhibit ethnic-specific associations with cardiovascular risk. However, their prognostic value for major adverse cardiovascular and cerebrovascular events (MACCE) in Asian populations remains undefined. This prospective cohort study enrolled 1969 patients (mean age 54.5 ± 10.7 years, 60.2% male) with hyperlipidemia and followed them for a median...

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Source

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Identifiers

PMID: 40820643
DOI: 10.1111/jch.70120
PMCID: PMC12358678

Genes

PCSK9
TG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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