Article
Artificial Intelligence-Estimated Intrapancreatic Fat and Its Relationship to Familial and Germline Pancreatic Cancer Risk.
United European gastroenterology journal - 1 Sept 2026
Konikoff Tom, Janssens Laurens P, Takahashi Hiroaki, Suman Garima, Nugen Fred, Mishra Anup, Korfiatis Panos, Carlson Erin E, Bamlet William R, Pradeep Aishwarya, Harper Kelly, Doering Karen A, Delgado Adriana, Erickson Bradley J, Goenka Ajit H, Takahashi Naoki, Oberg Ann L, Majumder Shounak
Abstract excerpt
BACKGROUND: Family history of pancreatic cancer (PC), pathogenic germline variants (PGVs), and increased intrapancreatic fat (IPF) are individually associated with increased PC risk. Whether IPF is elevated in high-risk individuals (HRIs) with PC family history or PGVs is unknown. Although MRI is the preferred modality for IPF measurement, region-of-interest-based approaches are prone to sampling bias because...
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