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Article

Effect of longevity genotype on acute phase response to a lipopolysaccharide challenge in dairy goats.

PloS one - 1 Jan 2026

Ithurbide Marie, Rupp Rachel, Fassier Thierry, Friggens Nicolas C, Foucras Gilles

Abstract excerpt

The present study aims to explore the phenotypic variability of the inflammatory response to a lipopolysaccharide (LPS) challenge in goats and compare the reaction between two lines divergently selected for functional longevity. Hyper-selection based on functional longevity successfully created two groups of goats with different lifespans (High_LGV and Low_LGV). Primiparous goats were injected intravenously with...

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Identifiers

PMID: 42664276
DOI: 10.1371/journal.pone.0356779
PMCID: PMC13524232

Genes

IL4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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