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Article

In vivo relevance of polymorphic Interleukin 8 promoter haplotype for the systemic immune response to LPS in Holstein-Friesian calves.

Veterinary immunology and immunopathology - 1 Dec 2016

Stojkovic Bojan, McLoughlin Rachel M, Meade Kieran G

Abstract excerpt

Interleukin 8, also known as CXC chemokine ligand 8 (CXCL8), is a critical chemokine in the recruitment of leukocytes to sites of infection and is a potent mediator of inflammation. We previously discovered 29 polymorphic sites in the promoter region of the bovine Interleukin 8 gene, which segregate into two distinct haplotypes, denoted IL8-h1 and IL8-h2. Population genetic analysis of these two haplotypes showed...

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Source

Identifiers

PMID: 27863538
DOI: 10.1016/j.vetimm.2016.09.006

Genes

CXCL8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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