Dual PCR-Sanger Sequencing Assay for Simultaneous sqle-Based Identification and Resistance Detection in Trichophyton Species.

doi:10.3201/eid3209.260819

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Dual PCR-Sanger Sequencing Assay for Simultaneous sqle-Based Identification and Resistance Detection in Trichophyton Species.

Emerging infectious diseases - 1 Sept 2026

Abou-Chakra Nissrine, Jørgensen Karin M, Astvad Karen Marie Thyssen, Arendrup Maiken Cavling

Abstract excerpt

Trichophyton fungal infections are common and increasingly complicated by terbinafine resistance. To support accurate molecular identification and resistance profiling, we provide a validated dataset of full-length squalene epoxidase (sqle) gene sequences from 493 Trichophyton isolates representing 18 species, addressing limited availability and misannotation of sqle sequences in public databases, particularly...

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PMID: 42661146
DOI: 10.3201/eid3209.260819

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.