Looking back on the history of epidermal growth factor receptor mutations in lung cancer.

doi:10.1098/rstb.2024.0506

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Looking back on the history of epidermal growth factor receptor mutations in lung cancer.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 27 Aug 2026

Herbst Roy S, Wang Meina, Politi Katerina

Abstract excerpt

The discovery of the epidermal growth factor receptor (EGFR) represents a landmark achievement in biomedical science, laying the foundation for one of the most transformative success stories in oncology. From the early isolation of epidermal growth factor (EGF) by Stanley Cohen and colleagues to the cloning of EGFR and its identification as a receptor tyrosine kinase, these pioneering studies revealed its central...

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PMID: 42656148
DOI: 10.1098/rstb.2024.0506

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EGFR
EGF

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