Article
Quasispecies and its impact on viral hepatitis.
Virus research - 1 Aug 2007
Domingo Esteban, Gomez Jordi
Abstract excerpt
Quasispecies dynamics mediates adaptability of RNA viruses through a number of mechanisms reviewed in the present article, with emphasis on the medical implications for the hepatitis viruses. We discuss replicative and non-replicative molecular mechanisms of genome variation, modulating effects of mutant spectra, and several modes of viral evolution that can affect viral pathogenesis. Relevant evolutionary events...
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