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Article

What a Difference a Gene Makes: Identification of Virulence Factors of Cowpox Virus.

Journal of virology - 6 Jan 2020

Tamošiūnaitė Aistė, Weber Saskia, Schippers Timo, Franke Annika, Xu Zhiyong, Jenckel Maria, Pfaff Florian, Hoffmann Donata, Newell Maegan, Tischer B Karsten, Beer Martin, Osterrieder Nikolaus

Abstract excerpt

Cowpox virus (CPXV) is a zoonotic orthopoxvirus (OPV) that causes spillover infections from its animal hosts to humans. In 2009, several human CPXV cases occurred through transmission from pet rats. An isolate from a diseased rat, RatPox09, exhibited significantly increased virulence in Wistar rats and caused high mortality compared to that caused by the mildly virulent laboratory strain Brighton Red (BR). The...

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Identifiers

PMID: 31645446
DOI: 10.1128/JVI.01625-19
PMCID: PMC6955266

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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