Patient-Level KRAS G12C Prevalence among Hispanic/Latino and Non-Hispanic White Patients in Real-world Clinicogenomic Cohorts.

doi:10.1158/2767-9764.CRC-26-0322

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Article

Patient-Level KRAS G12C Prevalence among Hispanic/Latino and Non-Hispanic White Patients in Real-world Clinicogenomic Cohorts.

Cancer research communications - 1 Sept 2026

Pilco-Janeta Daniel F, De la Cruz-Puebla Myriam, Guamán-Pilco Daisy R, Montenegro Diego, Miranda William

Abstract excerpt

KRAS G12C is a treatment-defining biomarker in non-small cell lung cancer (NSCLC), particularly lung adenocarcinoma. Hispanic/Latino (H/L) patients remain undercharacterized in precision oncology datasets, and patient-level KRAS G12C prevalence has not been consistently quantified using strict ethnicity definitions. We analyzed MSK-CHORD as the initial reference cohort and American Association for Cancer Research...

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Topics

Aged
Female
Humans
Male
Middle Aged
Adenocarcinoma of Lung
Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Cohort Studies

Hispanic or Latino

Lung Neoplasms

Mutation

Prevalence

Proto-Oncogene Proteins p21(ras)

White

Source

Open in PubMed Open full text

Identifiers

PMID: 42641173
DOI: 10.1158/2767-9764.CRC-26-0322
PMCID: PMC13548115

Genes

KRAS

Variants

Provenance

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