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Article

Genetic and autoimmune predispositions to fulminant viral hepatitis in children.

Frontiers in immunology - 1 Jan 2026

Bousfiha Mohamed, Ben Sabbahia Dalal, Jouanguy Emmanuelle, Casanova Jean-Laurent, El Bakkouri Jalila, Bousfiha Ahmed Aziz, Amenzoui Naima

Abstract excerpt

Fulminant viral hepatitis (FVH) in children is a rare but often fatal form of acute liver failure occurring in the absence of preexisting liver disease. Its exceptional incidence during otherwise common viral infections, including hepatitis A virus (HAV), hepatitis B virus (HBV), and herpes simplex virus (HSV), supports a decisive role for host susceptibility. Recent advances in human immunogenetics delineate two...

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Identifiers

PMID: 42630887
DOI: 10.3389/fimmu.2026.1858895
PMCID: PMC13494751

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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