Article
Chromatin immunoprecipitation assay for analyzing histone H3-mediated regulation of copper homeostasis.
Methods in enzymology - 1 Jan 2026
Singh Sakshi, Sahu Rakesh Kumar, Tomar Raghuvir Singh
Abstract excerpt
Histone tails undergo various post-translational modifications that aid in recruiting effector proteins involved in diverse transcriptional responses. Our previous work explored the role of histone H3 N-terminal residues and their modifications on the transcriptional regulation of the CUP1 metallothionein gene during cellular copper stress. To pinpoint critical histone residues, we used complementary methods,...
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