Article
Heat shock transcription factor activates transcription of the yeast metallothionein gene.
Molecular and cellular biology - 1 Mar 1991
Silar P, Butler G, Thiele D J
Abstract excerpt
In the yeast Saccharomyces cerevisiae, transcription of the metallothionein gene CUP1 is induced by copper and silver. Strains with a complete deletion of the ACE1 gene, the copper-dependent activator of CUP1 transcription, are hypersensitive to copper. These strains have a low but significant basal level of CUP1 transcription. To identify genes which mediate basal transcription of CUP1 or which activate CUP1 in...
Topics
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- DNA-Binding Proteins
- Gene Expression Regulation, Fungal
- Heat-Shock Proteins
- Metallothionein
- Molecular Sequence Data
- Mutation
- Regulatory Sequences, Nucleic Acid
- Restriction Mapping