Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

African genetic diversity and adaptation inform a precision medicine agenda.

Nature reviews. Genetics - 1 May 2021

Pereira Luisa, Mutesa Leon, Tindana Paulina, Ramsay Michèle

Abstract excerpt

The deep evolutionary history of African populations, since the emergence of modern humans more than 300,000 years ago, has resulted in high genetic diversity and considerable population structure. Selected genetic variants have increased in frequency due to environmental adaptation, but recent exposures to novel pathogens and changes in lifestyle render some of them with properties leading to present health...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black People
Share to Evolution, Molecular
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Genetics, Population

Share to Precision Medicine

Source

Identifiers

PMID: 33432191
DOI: 10.1038/s41576-020-00306-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

African genetic diversity and adaptation inform a precision medicine agenda.PMID 33432191Read ↗

High-depth African genomes inform human migration and health.Semantic proximity Read ↗

Pharmacogenomic implications of the evolutionary history of infectious diseases in Africa.Semantic proximity Read ↗

African genetic diversity provides novel insights into evolutionary history and local adaptations.Semantic proximity Read ↗

Africa: continent of genome contrasts with implications for biomedical research and health.Semantic proximity Read ↗

The Emergence of Genomic Research in Africa and New Frameworks for Equity in Biomedical ResearchSemantic proximity Read ↗

The genomic landscape of African populations in health and disease.Semantic proximity Read ↗

African genetic diversity: implications for human demographic history, modern human origins, and complex disease mapping.Semantic proximity Read ↗

The Critical Needs and Challenges for Genetic Architecture Studies in AfricaSemantic proximity Read ↗

Genetic variation and adaptation in Africa: implications for human evolution and disease.Semantic proximity Read ↗

Genetic studies of African populations: an overview on disease susceptibility and response to vaccines and therapeutics.Semantic proximity Read ↗

Inferences of African evolutionary history from genomic data.Semantic proximity Read ↗

Enriching African genome representation through the AGenDA project.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.