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Article

GWAS links APOE to neuropsychiatric symptoms in mild cognitive impairment and dementia.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Jun 2025

Vattathil Selina M, Blostein Freida, Miller-Fleming Tyne W, Davis Lea K, Wingo Thomas S, Wingo Aliza P

Abstract excerpt

INTRODUCTION: Neuropsychiatric symptoms in dementia (NPS) collectively refer to behavioral and psychological symptoms affecting individuals with mild cognitive impairment (MCI) or Alzheimer's disease or related dementia (ADRD). NPS are among the most troubling aspects of living with dementia but their treatments have limited efficacy. We aim to investigate genetic variants contributing to NPS to identify new...

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Source

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Identifiers

PMID: 40495575
DOI: 10.1002/alz.70329
PMCID: PMC12152374

Genes

NPS
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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