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Article

Over-Representation of Sperm-Associated Deleterious Mutations Across Wild and Ex Situ Cheetah (Acinonyx jubatus) Populations.

Molecular ecology - 1 Aug 2026

Peers Jessica A, Sibley Heather R, Armstrong Ellie E, Crosier Adrienne E, Nash Will J, Koepfli Klaus-Peter, Haerty Wilfried

Abstract excerpt

As purifying selection becomes less effective and inbreeding increases, small populations frequently develop an increased load of genome-wide deleterious mutations. Reflecting this pattern, deleterious mutations in genes associated with fertility and immunity have previously been identified in the cheetah (Acinonyx jubatus), which has had a low effective population size for at least the last 10,000 years....

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PMID: 42605495
DOI: 10.1111/mec.70513
PMCID: PMC13478778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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