Article
Genomic legacy of the African cheetah, Acinonyx jubatus.
Genome biology - 10 Dec 2015
Dobrynin Pavel, Liu Shiping, Tamazian Gaik, Xiong Zijun, Yurchenko Andrey A, Krasheninnikova Ksenia, Kliver Sergey, Schmidt-Küntzel Anne, Koepfli Klaus-Peter, Johnson Warren, Kuderna Lukas F K, García-Pérez Raquel, Manuel Marc de, Godinez Ricardo, Komissarov Aleksey, Makunin Alexey, Brukhin Vladimir, Qiu Weilin, Zhou Long, Li Fang, Yi Jian, Driscoll Carlos, Antunes Agostinho, Oleksyk Taras K, Eizirik Eduardo, Perelman Polina, Roelke Melody, Wildt David, Diekhans Mark, Marques-Bonet Tomas, Marker Laurie, Bhak Jong, Wang Jun, Zhang Guojie, O'Brien Stephen J
Abstract excerpt
BACKGROUND: Patterns of genetic and genomic variance are informative in inferring population history for human, model species and endangered populations. RESULTS: Here the genome sequence of wild-born African cheetahs reveals extreme genomic depletion in SNV incidence, SNV density, SNVs of coding genes, MHC class I and II genes, and mitochondrial DNA SNVs. Cheetah genomes are on average 95 % homozygous compared...
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