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Article

Migraine immune cell gene targets and their relationship to psychiatric disorders.

The journal of headache and pain - 25 Jul 2026

Mo Xin, Sun Dongren, Li Fangfang, Wang Danqi, Deng Yunjiao, Liao Yiwei, Yang Xiaosu, Zhao Haiting

Abstract excerpt

BACKGROUND: Migraine frequently co-occurs with psychiatric disorders, yet the immunogenetic mechanisms linking these conditions remain largely unexplored. METHODS: Using cis-eQTL data from 28 immune cell subtypes (1,925 donors) and GWAS summary statistics for migraine and five psychiatric disorders, we performed single-cell transcriptome-wide Mendelian randomization, Bayesian colocalization, genetic correlation,...

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Identifiers

PMID: 42581340
DOI: 10.1186/s10194-026-02465-1
PMCID: PMC13464352

Genes

CDK2AP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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