Article
Multibehavioral Phenotyping in Early-Life-Stage Zebrafish for Identifying Disruptors of Nonassociative Learning.
Environmental health perspectives - 4 Aug 2026
Leuthold David, Herold Nadia K, Nerlich Jana, Bartmann Kristina, Scharkin Ilka, Hallermann Stefan J, Schweiger Nicole, Fritsche Ellen, Tal Tamara
Abstract excerpt
BACKGROUND: The vertebrate nervous system is vulnerable to chemical toxicity, and the widespread release of chemicals into the environment outstrips the capacity to assess their safety. The zebrafish (Danio rerio) is a powerful vertebrate model that can bridge the gap between in vitro- and mammalian-based in vivo studies. However, the behavior-rich repertoire of larval zebrafish, a 3R-compliant model amenable to...
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