Article
Integrative assessment of benzene exposure to Caenorhabditis elegans using computational behavior and toxicogenomic analyses.
Environmental science & technology - 15 Jul 2014
Eom Hyun-Jeong, Kim Hungsoo, Kim Bo-Moon, Chon Tae-Soo, Choi Jinhee
Abstract excerpt
In this study, we investigated the toxic effects of benzene to the nematode Caenorhabditis elegans in an integrative manner, using computational behavior and toxicogenomics analyses, along with survival and reproduction. Benzene exposure led to changes in locomotive behavior and reproduction decline in C. elegans. Microarray followed by pathway analysis revealed that 228 genes were differentially expressed by...
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