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Article

SR9009 regulates macrophage polarization via the NR1D1/NF-κB axis to ameliorate obesity-associated ulcerative colitis

23 Jul 2026

Abstract excerpt

Abstract Objective The incidence of ulcerative colitis (UC) and obesity has risen in recent years, potentially linked through metabolic dysregulation and chronic inflammation. The nuclear receptor NR1D1 is pivotal in regulating circadian rhythms and plays a significant role in inflammation and metabolism. This study investigates the therapeutic effects and mechanisms of the NR1D1 agonist SR9009 on obesity-related...

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Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Helicobacter pylori-related gastroenterology studies
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PMID: 42564045
DOI: 10.3389/fgstr.2026.1762028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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