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Article

Nuclear Receptors Regulate Intestinal Inflammation in the Context of IBD

14 May 2019

Abstract excerpt

Gastrointestinal (GI) homeostasis is strongly dependent on nuclear receptor (NR) functions. They play a variety of roles ranging from nutrient uptake, sensing of microbial metabolites, regulation of epithelial intestinal cell integrity to shaping of the intestinal immune cell repertoire. Several NRs are associated with GI pathologies; therefore, systematic analysis of NR biology, the underlying molecular...

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PMID: 31139192
DOI: 10.3389/fimmu.2019.01070

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