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Article

The application value of serous cavity effusion supernatant in multi-driver gene detection for non-small cell lung cancer.

Annals of diagnostic pathology - 1 Dec 2026

Dong Lvli, Cao Yaqian, Liu Ying, Du Yun

Abstract excerpt

Obtaining tissue from advanced non-small cell lung cancer(NSCLC) patients is difficult, yet mutation testing is crucial for targeted therapy. This study evaluates the clinical utility of serous cavity effusion (SCE) supernatant for multi-gene mutation testing, comparing its performance with cell blocks as a promising liquid biopsy alternative. SCE samples were collected from untreated NSCLC patients. Following...

Read the complete abstract on PubMed

Topics

Humans
Carcinoma, Non-Small-Cell Lung
Lung Neoplasms
Female
Mutation
DNA Mutational Analysis
Male

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Middle Aged

Aged

Liquid Biopsy

Biomarkers, Tumor

Adult

Source

Identifiers

PMID: 42556090
DOI: 10.1016/j.anndiagpath.2026.152696

Genes

ALK
BRAF
EGFR
KRAS
MET
NTRK1
RET
ROS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

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