Article
Development of a Point-of-Care Recombinase Polymerase Amplification Assay for Detection of Neisseria gonorrhoeae and Ceftriaxone-Resistance Associated penA Allele 60.001.
Molecular diagnosis & therapy - 1 Sept 2026
Sun Xia, Fu Ying, Liu Yi, Liu Qiongyao, Chen Luxia, Zhu Jiang, Lin Xu'ai, Cheng Hao, van der Veen Stijn
Abstract excerpt
BACKGROUND: Neisseria gonorrhoeae is a global public health threat, exacerbated by the rapid dissemination of ceftriaxone-resistant strains harboring penA allele 60.001. Current diagnostics are limited by long turnaround times, reliance on thermal cycling equipment, and poor suitability for resource-limited settings. METHODS: We developed an isothermal recombinase polymerase amplification assay coupled with a...
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