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Recombination mapping identifies a commensal Neisseria subflava origin of mosaic penA 60.001 allele in Neisseria gonorrhoeae.

FEMS microbiology letters - 7 Jan 2026

Kanesaka Izumo, Ohno Akira, Laumen Jolein Gyonne Elise, Abdellati Saïd, de Block Tessa, Morita Masahiro, Katsuse Akiko Kanayama, Kobayashi Intetsu, Kenyon Chris, Manoharan-Basil Sheeba Santhini

Abstract excerpt

The emergence of ceftriaxone resistance in Neisseria gonorrhoeae (FC428 clone) has been linked to the acquisition of mosaic penA alleles, yet the origin of the mosaic penA 60.001 alleles and the contribution of commensal Neisseria as genetic donors remain incompletely resolved. We analysed the penA gene from 29 commensal Neisseria isolates collected from adults in Tokyo between 2018 and 2023 and compared these...

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PMID: 42315487
DOI: 10.1093/femsle/fnag071

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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