Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[General anatomic and histopathological diagnostic aspects of hereditary tumor syndromes : The role of pathology].

Pathologie (Heidelberg, Germany) - 1 Sept 2026

Agaimy Abbas, Hartmann Arndt

Abstract excerpt

With the widely increasing implementation of modern next generation sequencing (NGS) technologies in routine molecular pathology practice, the fraction of cancers with a definite or probable hereditary background has been steadily increasing. Currently, it is assumed that 5-10% of all malignancies develop in the context of germline predisposition diseases. Not rarely, the diagnosis and recognition of cancer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Renal Cell
Share to Gastrointestinal Stromal Tumors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to FAP gene

Share to FH gene

Share to Genetic Predisposition to Disease

Share to Kidney Neoplasms

Share to Neoplastic Syndromes, Hereditary

Source

Identifiers

PMID: 42489911
DOI: 10.1007/s00292-026-01581-8

Genes

FH
FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[General anatomic and histopathological diagnostic aspects of hereditary tumor syndromes : The role of pathology].PMID 42489911Read ↗

Uncovering Hereditary Tumor Syndromes: Emerging Role of Surgical Pathology.Semantic proximity Read ↗

Hereditary and Familial Tumor Syndromes: When to Think of Them? The Emerging Role of Pathologists as Sentinels of Genetic Cancer Predisposition.Semantic proximity Read ↗

Morphological clues to the appropriate recognition of hereditary renal neoplasms.Semantic proximity Read ↗

From Familial Clustering to a Dedicated Classification: The Historical Recognition of Hereditary Tumor Syndromes in the WHO Classification of Tumors.Semantic proximity Read ↗

10 rare tumors that warrant a genetics referral.Semantic proximity Read ↗

[Hereditary kidney cancers: The pathologist's view in 2020].Semantic proximity Read ↗

Hereditary Endocrine Tumor Syndromes: The Clinical and Predictive Role of Molecular HistopathologySemantic proximity Read ↗

[Clinical Cancer Genetics: A guide for the pathologist].Semantic proximity Read ↗

Hereditary Renal Cancer Syndromes: Clinicopathologic Features and Correlation With Tumors Harboring Somatic Mutations.Semantic proximity Read ↗

The Role of the Surgical Pathologist in the Recognition of Hereditary SDH-Deficient Tumor Syndromes.Semantic proximity Read ↗

Novel morphological and genetic features of fumarate hydratase deficient renal cell carcinoma in HLRCC syndrome patients with a tailored therapeutic approachSemantic proximity Read ↗

Utility of prospective pathologic evaluation to inform clinical genetic testing for hereditary leiomyomatosis and renal cell carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.