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Article

Genomic landscape of Mexican patients with maturity onset diabetes of the young: beyond mutations in MODY-known genes.

Frontiers in endocrinology - 1 Jan 2026

Moscona-Nissan Alberto, Marrero-Rodríguez Daniel, Andonegui-Elguera Sergio, Luna-Ávila Eduardo Salif, Martínez-Mendoza Florencia, Vela-Patiño Sandra, Ramírez-Ramos Itzel, Hinojosa-Alvarez Silvia, Hernandez-Perez Jesus, Chavez-Santoscoy Rocio A, Mercado-Medrez Sophia, León-Wu Kapy S, De Miguel-Ibáñez Regina, Mercado Moisés, Taniguchi-Ponciano Keiko, Ferreira-Hermosillo Aldo

Abstract excerpt

Introduction: Maturity Onset Diabetes of the Young (MODY) remains an underdiagnosed condition with remarkable genetic variability across populations. While diagnostic tools are based on Caucasian cohorts, Whole Exome Sequencing (WES) studies are needed to identify new genes in non-Caucasians, as up to 77% of patients do not harbor variants of significance in MODY-known genes. No WES studies have addressed the...

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Identifiers

PMID: 42460311
DOI: 10.3389/fendo.2026.1887861
PMCID: PMC13368645

Genes

KCNJ12
MAP2K3
PEX5
SYT15
TPTE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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