Article
Whole‑exome sequencing in Russian children with non‑type 1 diabetes mellitus reveals a wide spectrum of genetic variants in MODY‑related and unrelated genes.
Molecular medicine reports - 1 Dec 2019
Glotov Oleg S, Serebryakova Elena A, Turkunova Mariia E, Efimova Olga A, Glotov Andrey S, Barbitoff Yury A, Nasykhova Yulia A, Predeus Alexander V, Polev Dmitrii E, Fedyakov Mikhail A, Polyakova Irina V, Ivashchenko Tatyana E, Shved Natalia Y, Shabanova Elena S, Tiselko Alena V, Romanova Olga V, Sarana Andrey M, Pendina Anna A, Scherbak Sergey G, Musina Ekaterina V, Petrovskaia-Kaminskaia Anastasiia V, Lonishin Liubov R, Ditkovskaya Liliya V, Zhelenina Liudmila А, Tyrtova Ludmila V, Berseneva Olga S, Skitchenko Rostislav K, Suspitsin Evgenii N, Bashnina Elena B, Baranov Vladislav S
Abstract excerpt
The present study reports on the frequency and the spectrum of genetic variants causative of monogenic diabetes in Russian children with non‑type 1 diabetes mellitus. The present study included 60 unrelated Russian children with non‑type 1 diabetes mellitus diagnosed before the age of 18 years. Genetic variants were screened using whole‑exome sequencing (WES) in a panel of 35 genes causative of maturity onset...
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