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Article

Impact of BRAF inhibitors on surgical outcomes in melanoma brain metastases: Evidence from a multicenter observational study.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Oct 2026

Armocida Daniele, Bianconi Andrea, Carbone Francesco, Leone Augusto, D'Amico Alberto, Pesce Alessandro, Cofano Fabio, Fiaschi Pietro, Salvati Maurizio, Zona Gianluigi, Denaro Luca, Frati Alessandro, Spetger Uwe, Rudà Roberta, Minniti Giuseppe, Garbossa Diego, Ius Tamara

Abstract excerpt

BACKGROUND: Melanoma brain metastases (MBMs) pose significant clinical challenges, associated with high morbidity and mortality. Treatment with the BRAF inhibitors has demonstrated long-term clinical benefit, although data regarding their efficacy in surgical MBM patients remain limited. METHODS: The study assesses the experience of 5 institutions with patients surgically treated for MBM. Clinical, treatment and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42456530
DOI: 10.1016/j.jocn.2026.112185

Genes

BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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