Article
Impact of BRAF mutation and BRAF inhibition on melanoma brain metastases.
Melanoma research - 1 Feb 2015
Gummadi Tulasi, Zhang Ben Y, Valpione Sara, Kim Chul, Kottschade Lisa A, Mittapalli Rajendar K, Chiarion-Sileni Vanna, Pigozzo Jacopo, Elmquist William F, Dudek Arkadiusz Z
Abstract excerpt
The impact of BRAF mutations in metastatic melanoma on the incidence of brain metastases and melanoma prognosis and the effect of BRAF inhibitors on the incidence of brain metastases has not been defined. Therefore, a retrospective analysis of patients with metastatic melanoma treated at three institutions was carried out to examine the impact of BRAF mutations and a BRAF inhibitor, vemurafenib, on the incidence...
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