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Article

New candidate reference measurement procedure for NRAS p.Q61R quantification by digital PCR.

Methods (San Diego, Calif.) - 1 Oct 2026

Petiti Jessica, Caria Sabrina, Revel Laura, Bogožalec Košir Alexandra, Carrà Giovanna, Fava Marika, Weiss Nathalie, Kremser Marcel, Gillmeister Marit, Vierbaum Laura, Kaufmann-Stoeck Anne, Schmitz Arthur, Milavec Mojca, Divieto Carla

Abstract excerpt

Accurate and comparable quantification of somatic mutations is essential for precision oncology, as clinical decision-making increasingly relies on the quantification of molecular biomarkers. Despite major technological advances, inter-laboratory variability and the lack of metrological traceability remain significant barriers to harmonization and confidence in mutation testing results. Reference Measurement...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42431334
DOI: 10.1016/j.ymeth.2026.07.005

Genes

NRAS

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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