Article
[Utility of next-generation sequencing for diagnosing non-secretory multiple myeloma].
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2026
Sota Mana, Nakano Hirofumi, Imai Yui, Uchida Tomonori, Inoue Morihiro, Murakami Koichi, Kim Haryoon, Mizuno Kota, Ito Yuta, Kogure Yasunori, Kataoka Keisuke, Hagihara Masao
Abstract excerpt
A 62-year-old man was referred to our hospital for leukocytosis with an increase (25.5%) of plasma cell-like cells in the peripheral blood. M-protein was not detected, and no deviation of the κ/λ ratio of free light chain was observed. Bone marrow biopsy showed increased plasma cell-like cell counts; however, immunohistochemical staining was positive only for CD138, and negative for both κ and λ chains....
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