Article
Leptomeningeal Myelomatosis: A Rare but Devastating Manifestation of Multiple Myeloma Diagnosed Using Cytology, Flow Cytometry, and Fluorescent in situ Hybridization.
Acta haematologica - 1 Jan 2000
Bommer Martin, Kull Miriam, Teleanu Veronica, Schwarzwälder Phyllis, Feuring-Buske Manuela, Kroenke Jan, Bunjes Donald, Langer Christian
Abstract excerpt
INTRODUCTION: Involvement of the central nervous system in patients with multiple myeloma is a rare event. We evaluated the diagnostic workup and prognosis of patients with leptomeningeal myelomatosis (LMM). METHODS: Between April 2005 and April 2016, we identified 16 cases with LMM. The involvement was diagnosed by magnetic resonance imaging (MRI), cerebrospinal fluid (CSF) cytology as well as flow cytometry....
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