Article
Paediatric macrophage activation syndrome: clinical features and outcomes across diverse aetiologies.
Rheumatology (Oxford, England) - 30 Jun 2026
Türkmen Şeyma, Tuğrul Hazal Ceren, Yarar Murat Hakkı, Eser Metin, Atay Gürkan, Erdoğan Seher, Sözeri Betül
Abstract excerpt
OBJECTIVES: To characterize clinical features and outcomes of paediatric macrophage activation syndrome (MAS) and examine associations with immune-regulatory genetic variation. METHODS: This retrospective study included 120 children with MAS. Clinical, laboratory and outcome data were analysed. A subgroup underwent genetic testing for Hemophagocytic Lymphohistiocytosis (HLH)-related variants. Multivariable...
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