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Article

Macrophage Activation Syndrome: different mechanisms leading to a one clinical syndrome.

Pediatric rheumatology online journal - 17 Jan 2017

Bracaglia Claudia, Prencipe Giusi, De Benedetti Fabrizio

Abstract excerpt

BACKGROUND: Macrophage activation syndrome (MAS) is a severe complication of rheumatic disease in childhood, particularly in systemic Juvenile Idiopathic Arthritis (sJIA). It is characterize by an uncontrolled activation and proliferation of T lymphocytes and macrophages. MAIN CONTENT: MAS is currently classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH). The reason is...

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Identifiers

PMID: 28095869
DOI: 10.1186/s12969-016-0130-4
PMCID: PMC5240371

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