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Article

Macrophage activation syndrome: advances towards understanding pathogenesis

30 May 2010

Abstract excerpt

PURPOSE OF REVIEW: Macrophage activation syndrome (MAS), a major cause of morbidity and mortality in pediatric rheumatology, is most strongly associated with systemic juvenile idiopathic arthritis (SJIA). There are no validated diagnostic criteria and early diagnosis is difficult. This review summarizes the progress in understanding of MAS pathophysiology that may help define specific diagnostic biomarkers....

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PMID: 20517154
DOI: 10.1097/01.bor.0000381996.69261.71

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