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Article

AKT-mTOR/P53 PathwayDriven RapamycinAlpelisib Efficacy in Animal Models of TIE2Mutant Venous Malformations.

Frontiers in bioscience (Landmark edition) - 1 Jun 2026

Li Yi, He Yang, Lin Jian, Wang Tong, Wang Wei, Tang Zhencun

Abstract excerpt

BACKGROUND: Sporadic venous malformations are a prevalent vascular anomaly in the oral and maxillofacial region. Current therapeutic strategies are associated with high recurrence rates and limited applicability in critical anatomical regions. Therefore, there is a pressing demand for more effective treatment modalities to address these challenges. METHODS: This study utilized transcriptome sequencing to analyze...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42411503
DOI: 10.31083/FBL48694

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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